The Role of Oxidants and Antioxidants in Chronic Tonsillitis

R. Chethana, P. P. Devan, K. Sushmitha

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


The aim of the study was to determine the possible role of oxidants and antioxidants in chronic tonsillitis in paediatric age group and also to know the outcome of tonsillectomy on the oxidative stress 60 patients (30 tests, 30 controls) in the age group 3–14 years were recruited in the study. Total antioxidant capacity, superoxide dismutase (antioxidants), Malondialdehyde (oxidant) was measured from the venous blood sample. In the study group, i.e. group with chronic tonsillitis who were to undergo tonsillectomy, these levels were measured twice, preoperatively and 1 month after surgery. In the control group the parameters were measured only once. The results were compared statistically. Malondialdehyde levels (oxidant) levels in blood were siginificantly high in patients with chronic tonsillitis which reduced post tonsillectomy but did not normalise in 1 month after tonsillectomy. Total antioxidant capacity and superoxide dismutase levels (antioxidants) in blood were significantly low in patients with chronic tonsillitis which improved post tonsillectomy but did not normalize 1 month post-surgery. The study showed that oxidants and antioxidants have a role in chronic tonsillitis.Children with chronic tonsillitis are under significant oxidative stress. Reduction in oxidative stress post tonsillectomy suggested that the surgery was helpful in this respect.

Original languageEnglish
Pages (from-to)5269-5274
Number of pages6
JournalIndian Journal of Otolaryngology and Head and Neck Surgery
Publication statusPublished - 12-2022

All Science Journal Classification (ASJC) codes

  • Surgery
  • Otorhinolaryngology


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