Ticagrelor-Induced complete heart block: A rare entity

Wagle Varun Anand; Isha Khadke; R. Padmakumar; M. Sudhakar Rao; Bharti Chogtu

doi:10.4103/jpp.JPP_121_19

Ticagrelor-Induced complete heart block: A rare entity

Wagle Varun Anand, Isha Khadke, R. Padmakumar, M. Sudhakar Rao, Bharti Chogtu

Research output: Contribution to journal › Article › peer-review

Abstract

Ticagrelor, a purinergic P2Y12 receptor blocker, is a potent platelet antagonist and an important component in the treatment for acute coronary syndromes identified to have a potential risk to cause bradyarrhythmias. Here, we report the case of a diabetic patient of unstable angina with left bundle branch block who was prescribed ticagrelor post angioplasty. Electrocardiogram (ECG) revealed a complete heart block after about 1 week. Ticagrelor was stopped and replaced by clopidogrel. The patient became asymptomatic and ECG showed baseline rhythm after 1 week of stoppage of ticagrelor.

Original language	English
Pages (from-to)	75-77
Number of pages	3
Journal	Journal of Pharmacology and Pharmacotherapeutics
Volume	11
Issue number	2
DOIs	https://doi.org/10.4103/jpp.JPP_121_19
Publication status	Published - 01-04-2020

All Science Journal Classification (ASJC) codes

Pharmacology
Pharmacology (medical)

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10.4103/jpp.JPP_121_19

Cite this

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abstract = "Ticagrelor, a purinergic P2Y12 receptor blocker, is a potent platelet antagonist and an important component in the treatment for acute coronary syndromes identified to have a potential risk to cause bradyarrhythmias. Here, we report the case of a diabetic patient of unstable angina with left bundle branch block who was prescribed ticagrelor post angioplasty. Electrocardiogram (ECG) revealed a complete heart block after about 1 week. Ticagrelor was stopped and replaced by clopidogrel. The patient became asymptomatic and ECG showed baseline rhythm after 1 week of stoppage of ticagrelor. ",

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AU - Chogtu, Bharti

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AB - Ticagrelor, a purinergic P2Y12 receptor blocker, is a potent platelet antagonist and an important component in the treatment for acute coronary syndromes identified to have a potential risk to cause bradyarrhythmias. Here, we report the case of a diabetic patient of unstable angina with left bundle branch block who was prescribed ticagrelor post angioplasty. Electrocardiogram (ECG) revealed a complete heart block after about 1 week. Ticagrelor was stopped and replaced by clopidogrel. The patient became asymptomatic and ECG showed baseline rhythm after 1 week of stoppage of ticagrelor.

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Ticagrelor-Induced complete heart block: A rare entity

Abstract

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