TY - JOUR
T1 - Tunnel sign in patients with melioidosis
T2 - a case series from South India
AU - Gupta, Nitin
AU - Malla, Sundeep
AU - Kumar, Tirlangi Praveen
AU - Singh, Sonali
AU - Varma, Muralidhar
AU - Mukhopadhyay, Chiranjay
N1 - Publisher Copyright:
© The Author(s) 2024. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved.
PY - 2025/6/1
Y1 - 2025/6/1
N2 - Introduction: The tunnel sign (linear contrast enhancement along the corticospinal tract) can aid in the early diagnosis of neuromelioidosis, a potentially fatal condition requiring urgent diagnosis. Methodology: We retrospectively analyzed the hospital data of all patients with culture-confirmed melioidosis between 2018 and 2023 in a tertiary care hospital in South India. MRI scans of patients with neuromelioidosis were reviewed for the presence of the tunnel sign. Results: Of the 177 patients with melioidosis, 21 had possible neurological involvement. Seven had confirmed neuromelioidosis. Of the six patients with neuromelioidosis, where an MRI scan was available, a tunnel sign was noted in four. Conclusion: We report this study to create awareness amongst physicians to look for this sign in patients with suspected neuromelioidosis.
AB - Introduction: The tunnel sign (linear contrast enhancement along the corticospinal tract) can aid in the early diagnosis of neuromelioidosis, a potentially fatal condition requiring urgent diagnosis. Methodology: We retrospectively analyzed the hospital data of all patients with culture-confirmed melioidosis between 2018 and 2023 in a tertiary care hospital in South India. MRI scans of patients with neuromelioidosis were reviewed for the presence of the tunnel sign. Results: Of the 177 patients with melioidosis, 21 had possible neurological involvement. Seven had confirmed neuromelioidosis. Of the six patients with neuromelioidosis, where an MRI scan was available, a tunnel sign was noted in four. Conclusion: We report this study to create awareness amongst physicians to look for this sign in patients with suspected neuromelioidosis.
UR - https://www.scopus.com/pages/publications/105008083147
UR - https://www.scopus.com/pages/publications/105008083147#tab=citedBy
U2 - 10.1093/trstmh/trae097
DO - 10.1093/trstmh/trae097
M3 - Article
C2 - 39552317
AN - SCOPUS:105008083147
SN - 0035-9203
VL - 119
SP - 623
EP - 625
JO - Transactions of the Royal Society of Tropical Medicine and Hygiene
JF - Transactions of the Royal Society of Tropical Medicine and Hygiene
IS - 6
ER -
