TY - CHAP
T1 - Types of Raman Scattering Techniques for Neurodegenerative Diseases
AU - Kumari, Sparsha
AU - Shivakumar, Apoorva Bettagere
AU - Mehak, Sonam Fathima
AU - Mazumder, Nirmal
AU - Gangadharan, Gireesh
AU - Pillai, Vikram G.
N1 - Publisher Copyright:
© The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2022.
PY - 2022/1/1
Y1 - 2022/1/1
N2 - As human life expectancy has increased, age-related neurodegenerative disorders (NDs) are emerging as one of the greatest health and social threats of the twenty-first century. Most NDs manifest clinical symptoms at an advanced stage after the disease onset, making it difficult to detect before irreversible degenerative alterations in the brain occur. As a result, understanding the neural mechanisms and early detection of ND are crucial for enhancing human health and quality of life. Raman spectroscopy and microscopy techniques allow for label-free, video-rate data acquisition without any sample preparation, making them a viable tool for disease detection early on. Raman-based approaches can be employed in vivo for early diagnosis of NDs as they are noninvasive. They require simple instrumentation and enable non-destructive sample analysis, which makes them useful for real-time diagnosis. Here, we outline the various Raman spectroscopic and microscopic techniques with a special focus on their application as a diagnostic tool for neurodegenerative diseases.
AB - As human life expectancy has increased, age-related neurodegenerative disorders (NDs) are emerging as one of the greatest health and social threats of the twenty-first century. Most NDs manifest clinical symptoms at an advanced stage after the disease onset, making it difficult to detect before irreversible degenerative alterations in the brain occur. As a result, understanding the neural mechanisms and early detection of ND are crucial for enhancing human health and quality of life. Raman spectroscopy and microscopy techniques allow for label-free, video-rate data acquisition without any sample preparation, making them a viable tool for disease detection early on. Raman-based approaches can be employed in vivo for early diagnosis of NDs as they are noninvasive. They require simple instrumentation and enable non-destructive sample analysis, which makes them useful for real-time diagnosis. Here, we outline the various Raman spectroscopic and microscopic techniques with a special focus on their application as a diagnostic tool for neurodegenerative diseases.
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U2 - 10.1007/978-981-19-1352-5_3
DO - 10.1007/978-981-19-1352-5_3
M3 - Chapter
AN - SCOPUS:85160171766
SN - 9789811913518
SP - 39
EP - 57
BT - Advances in Brain Imaging Techniques
PB - Springer Nature
ER -
