TY - JOUR
T1 - Unraveling the Mysteries of Brain Cancer from Diagnosis to Treatment
AU - Mathure, Dyandevi
AU - Bhandare, Sejal
AU - Karati, Dipanjan
AU - Adnan, Mohammad
AU - Kumar, Dileep
N1 - Publisher Copyright:
© 2025 Bentham Science Publishers.
PY - 2025
Y1 - 2025
N2 - Even with recent advancements in surgery and multimodal adjuvant therapy, brain cancer treatment is still difficult. The blood-brain barrier and the potentially deadly medications' non-specificity have made pharmacological treatment for brain cancer particularly ineffective. The nanoparticle has surfaced as a viable brain delivery vector that can solve the issues with existing approaches. Furthermore, it is possible to integrate many functions into a single nanoplatform to enable tumor-specific diagnosis, therapy, and follow-up observation. Conventional technology does not allow for such multitasking. Recent developments in brain cancer treatment and detection using nanoparticles are discussed in this study. The benefits of delivery via nanoparticles are discussed, along with the kinds of nanoparticle systems being studied and their potential uses.
AB - Even with recent advancements in surgery and multimodal adjuvant therapy, brain cancer treatment is still difficult. The blood-brain barrier and the potentially deadly medications' non-specificity have made pharmacological treatment for brain cancer particularly ineffective. The nanoparticle has surfaced as a viable brain delivery vector that can solve the issues with existing approaches. Furthermore, it is possible to integrate many functions into a single nanoplatform to enable tumor-specific diagnosis, therapy, and follow-up observation. Conventional technology does not allow for such multitasking. Recent developments in brain cancer treatment and detection using nanoparticles are discussed in this study. The benefits of delivery via nanoparticles are discussed, along with the kinds of nanoparticle systems being studied and their potential uses.
UR - https://www.scopus.com/pages/publications/105005080088
UR - https://www.scopus.com/pages/publications/105005080088#tab=citedBy
U2 - 10.2174/0122117385331332241226101149
DO - 10.2174/0122117385331332241226101149
M3 - Review article
C2 - 39865818
AN - SCOPUS:105005080088
SN - 2211-7385
JO - Pharmaceutical Nanotechnology
JF - Pharmaceutical Nanotechnology
ER -