Urinary levels of biogenic atnine metabolites in mentally retarded children

K. NALINI; A. R. AROOR; A. RAO

doi:10.1111/j.1365-2788.1988.tb01432.x

Urinary levels of biogenic atnine metabolites in mentally retarded children

K. NALINI, A. R. AROOR, A. RAO^*

^*Corresponding author for this work

Department of Biochemistry, Kasturba Medical College, Manipal

Research output: Contribution to journal › Article › peer-review

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Abstract

ABSTRACT. Urinary total catecholamines, their metabolites and metabolite of serotonin were estimated in 32 mentally retarded children and 15 controls. Levels of total catecholamines. MHPG and 5‐HIAA were not significantly different from controls. However, the mean VMA and HVA excretion in mentally retarded children was significantly increased compared to the control group. It is concluded that an altered metabolism of dopamine is involved in mental retardation.

Original language	English
Pages (from-to)	419-424
Number of pages	6
Journal	Journal of Intellectual Disability Research
Volume	32
Issue number	5
DOIs	https://doi.org/10.1111/j.1365-2788.1988.tb01432.x
Publication status	Published - 01-01-1988

All Science Journal Classification (ASJC) codes

Rehabilitation
Arts and Humanities (miscellaneous)
Neurology
Clinical Neurology
Psychiatry and Mental health

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1365-2788.1988.tb01432.x

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abstract = "ABSTRACT. Urinary total catecholamines, their metabolites and metabolite of serotonin were estimated in 32 mentally retarded children and 15 controls. Levels of total catecholamines. MHPG and 5‐HIAA were not significantly different from controls. However, the mean VMA and HVA excretion in mentally retarded children was significantly increased compared to the control group. It is concluded that an altered metabolism of dopamine is involved in mental retardation.",

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AU - AROOR, A. R.

AU - RAO, A.

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N2 - ABSTRACT. Urinary total catecholamines, their metabolites and metabolite of serotonin were estimated in 32 mentally retarded children and 15 controls. Levels of total catecholamines. MHPG and 5‐HIAA were not significantly different from controls. However, the mean VMA and HVA excretion in mentally retarded children was significantly increased compared to the control group. It is concluded that an altered metabolism of dopamine is involved in mental retardation.

AB - ABSTRACT. Urinary total catecholamines, their metabolites and metabolite of serotonin were estimated in 32 mentally retarded children and 15 controls. Levels of total catecholamines. MHPG and 5‐HIAA were not significantly different from controls. However, the mean VMA and HVA excretion in mentally retarded children was significantly increased compared to the control group. It is concluded that an altered metabolism of dopamine is involved in mental retardation.

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Urinary levels of biogenic atnine metabolites in mentally retarded children

Abstract

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