TY - JOUR
T1 - Uterine malignant mixed müllerian tumor camouflaging as pelvic sarcoma
AU - Monappa, Vidya
AU - Kudva, Ranjini
AU - Hasan, Roumina
N1 - Publisher Copyright:
© 2015 Journal of Cancer Research and Therapeutics | Published by Wolters Kluwer - Medknow.
PY - 2015/10/1
Y1 - 2015/10/1
N2 - Malignant mixed Müllerian tumors (MMMTs) of the uterus are rare, aggressive tumors that present at an advanced stage and are associated with poor prognosis. They arise as a result of divergent carcinomatous and mesenchymal differentiation of tumor stem cells. Rarely one of the components may predominate contributing to diagnostic confusion. We present a rare case of uterine MMMT arising in endometrial adenocarcinoma, camouflaging as pelvic sarcoma with a major sarcomatous component. This case report highlights the importance of thorough tissue sampling and the role of immunohistochemistry (IHC) in arriving at an accurate diagnosis. This case also demonstrates the conversion theory of histogenesis of MMMTs.
AB - Malignant mixed Müllerian tumors (MMMTs) of the uterus are rare, aggressive tumors that present at an advanced stage and are associated with poor prognosis. They arise as a result of divergent carcinomatous and mesenchymal differentiation of tumor stem cells. Rarely one of the components may predominate contributing to diagnostic confusion. We present a rare case of uterine MMMT arising in endometrial adenocarcinoma, camouflaging as pelvic sarcoma with a major sarcomatous component. This case report highlights the importance of thorough tissue sampling and the role of immunohistochemistry (IHC) in arriving at an accurate diagnosis. This case also demonstrates the conversion theory of histogenesis of MMMTs.
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U2 - 10.4103/0973-1482.157325
DO - 10.4103/0973-1482.157325
M3 - Article
C2 - 26881567
AN - SCOPUS:84959526956
SN - 0973-1482
VL - 11
SP - 997
EP - 999
JO - Journal of Cancer Research and Therapeutics
JF - Journal of Cancer Research and Therapeutics
IS - 4
ER -