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Validation of an HPLC method for estimation of cefotaxime from dried blood spot: alternative to plasma-based PK evaluation in neonates
Bhim Bahadur Chaudhari
, Priyanka Sridhar
,
Sudheer Moorkoth
*
,
Leslie E. Lewis
,
Surulivelrajan Mallayasamy
*
Corresponding author for this work
Department of Pharmaceutical Quality Assurance, Manipal College of Pharmaceutical Sciences, Manipal
Department of Paediatrics, Kasturba Medical College, Manipal
Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal
Research output
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Contribution to journal
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Article
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peer-review
5
Citations (Scopus)
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INIS
evaluation
100%
blood
100%
validation
100%
plasma
100%
hplc
100%
neonates
100%
drugs
25%
populations
25%
antibiotics
25%
accuracy
25%
applications
12%
doses
12%
volume
12%
adults
12%
extraction
12%
correlations
12%
organs
12%
buffers
12%
acetonitrile
12%
precision
12%
sampling
12%
pediatrics
12%
carbon 8
12%
programming
12%
interchangeability
12%
Chemistry
High Performance Liquid Chromatography
100%
Cefotaxime
100%
Pharmacokinetics
14%
Buffer Solution
14%
Bioanalysis
14%
Plasma Method
14%
Acetonitrile
14%
Hematocrit
14%
Pharmacology, Toxicology and Pharmaceutical Science
High Performance Liquid Chromatography
100%
Cefotaxime
100%
Drug Analysis
14%
Acetonitrile
14%
Buffer
14%
Bacterial Infection
14%
Pharmacokinetics
14%