TY - JOUR
T1 - Vancomycin intermediate and vancomycin resistant staphylococcus aureus - mechanisms, clinical significance, and detection
AU - Kumari, Jyoti
AU - Shenoy, Shalini M.
AU - Hegde, Ashwini
AU - Vidyalakshmi, K.
AU - Chakrapani, M.
AU - Bhat, Gopalkrishna K.
N1 - Publisher Copyright:
© 2017 The Authors.
PY - 2017
Y1 - 2017
N2 - Vancomycin is used as the antibiotic of choice for severe infection caused by methicillin-resistant Staphylococcus aureus. Increased use of vancomycin and the selective pressure has resulted in the emergence of S. aureus with reduced susceptibility to vancomycin and vancomycin-resistant S. aureus. This review summarizes the definition, mechanism, clinical significance, and epidemiology of S. aureus with reduced susceptibility to vancomycin. It also discusses laboratory methods for detection and treatment options available for these pathogens.
AB - Vancomycin is used as the antibiotic of choice for severe infection caused by methicillin-resistant Staphylococcus aureus. Increased use of vancomycin and the selective pressure has resulted in the emergence of S. aureus with reduced susceptibility to vancomycin and vancomycin-resistant S. aureus. This review summarizes the definition, mechanism, clinical significance, and epidemiology of S. aureus with reduced susceptibility to vancomycin. It also discusses laboratory methods for detection and treatment options available for these pathogens.
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U2 - 10.22159/ajpcr.2017.v10i6.15993
DO - 10.22159/ajpcr.2017.v10i6.15993
M3 - Review article
AN - SCOPUS:85020872419
SN - 0974-2441
VL - 10
SP - 32
EP - 38
JO - Asian Journal of Pharmaceutical and Clinical Research
JF - Asian Journal of Pharmaceutical and Clinical Research
IS - 6
ER -