Vancomycin intermediate and vancomycin resistant staphylococcus aureus - mechanisms, clinical significance, and detection

Jyoti Kumari; Shalini M. Shenoy; Ashwini Hegde; K. Vidyalakshmi; M. Chakrapani; Gopalkrishna K. Bhat

doi:10.22159/ajpcr.2017.v10i6.15993

Vancomycin intermediate and vancomycin resistant staphylococcus aureus - mechanisms, clinical significance, and detection

Jyoti Kumari
, Shalini M. Shenoy
, Ashwini Hegde
, K. Vidyalakshmi
, M. Chakrapani
, Gopalkrishna K. Bhat^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

1 Citation (Scopus)

Abstract

Vancomycin is used as the antibiotic of choice for severe infection caused by methicillin-resistant Staphylococcus aureus. Increased use of vancomycin and the selective pressure has resulted in the emergence of S. aureus with reduced susceptibility to vancomycin and vancomycin-resistant S. aureus. This review summarizes the definition, mechanism, clinical significance, and epidemiology of S. aureus with reduced susceptibility to vancomycin. It also discusses laboratory methods for detection and treatment options available for these pathogens.

Original language	English
Pages (from-to)	32-38
Number of pages	7
Journal	Asian Journal of Pharmaceutical and Clinical Research
Volume	10
Issue number	6
DOIs	https://doi.org/10.22159/ajpcr.2017.v10i6.15993
Publication status	Published - 2017

All Science Journal Classification (ASJC) codes

Pharmacology
Pharmaceutical Science
Pharmacology (medical)

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10.22159/ajpcr.2017.v10i6.15993

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title = "Vancomycin intermediate and vancomycin resistant staphylococcus aureus - mechanisms, clinical significance, and detection",

abstract = "Vancomycin is used as the antibiotic of choice for severe infection caused by methicillin-resistant Staphylococcus aureus. Increased use of vancomycin and the selective pressure has resulted in the emergence of S. aureus with reduced susceptibility to vancomycin and vancomycin-resistant S. aureus. This review summarizes the definition, mechanism, clinical significance, and epidemiology of S. aureus with reduced susceptibility to vancomycin. It also discusses laboratory methods for detection and treatment options available for these pathogens.",

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AU - Kumari, Jyoti

AU - Shenoy, Shalini M.

AU - Hegde, Ashwini

AU - Vidyalakshmi, K.

AU - Chakrapani, M.

AU - Bhat, Gopalkrishna K.

PY - 2017

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AB - Vancomycin is used as the antibiotic of choice for severe infection caused by methicillin-resistant Staphylococcus aureus. Increased use of vancomycin and the selective pressure has resulted in the emergence of S. aureus with reduced susceptibility to vancomycin and vancomycin-resistant S. aureus. This review summarizes the definition, mechanism, clinical significance, and epidemiology of S. aureus with reduced susceptibility to vancomycin. It also discusses laboratory methods for detection and treatment options available for these pathogens.

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U2 - 10.22159/ajpcr.2017.v10i6.15993

DO - 10.22159/ajpcr.2017.v10i6.15993

M3 - Review article

AN - SCOPUS:85020872419

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JO - Asian Journal of Pharmaceutical and Clinical Research

JF - Asian Journal of Pharmaceutical and Clinical Research

IS - 6

ER -

Vancomycin intermediate and vancomycin resistant staphylococcus aureus - mechanisms, clinical significance, and detection

Abstract

All Science Journal Classification (ASJC) codes

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